In all these cases, there is a resulting increase in ventricular repolarizing current leading to a shortening of the APD, subsequent reduction in the ventricular refractory period and, as a consequence, a shortening of the QT interval.
The SCN8A mutation N1768D is a gain-of-function mutation that causes a large increase in persistent sodium current leading to neuronal hyperexcitability (9).
After a couple of lean years with the bat, Cook has been sensational for much of the last 12 months and that is reflected in him being the current leading Test run-scorer in 2015.
The current leading party in the National Assembly, the liberal United Democratic Party, appeared to have taken 81 seats, down sharply from the 136 seats it had controlled.
Anthony Franciosa, "the current leading man in Ava's fickle heart", as the paper put it, was the second man that night to attack Secchiaroli when he set off his flash.
Clear rounds for Skelton, Maher and Michael Whitaker on Wednesday should see them progress in the individual event, but they have work to do in terms of catching the current leading medal contenders that include American Kent Farrington, Germany's Christian Ahlmann and the 2008 Olympic champion, Eric Lamaze of Canada.
A few examples of this process: Dark matter and dark energy are the current leading topics in astronomy, as their discovery and controversy originated during the study of the galaxies.
Although both mutations resulted in an increased flow of current, leading to excessive excitatory drive and early onset EE, it was important to consider the different pathological mechanisms and drug targets when deciding treatment options.
Ajmal finished his spell as the current leading wicket-taker in Division Two with 63 scalps in nine matches, 21 more than Derbyshire's Mark Footitt, having hit his highest score, an unbeaten 53, earlier in the match.
Several of NBC's current leading ladies of comedy will also reportedly be in attendance.
