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Reflecting concerns over the assessment process expressed by disability charities, Harrington reported that "a number of the major charities … say that although they have seen some change for the better, it is disappointingly incomplete in coverage and depth.
An overall improvement in coverage and depth was observed with V.2, although the maximum coverage by design (100%) was not achieved.
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Further, health insurance remains limited in coverage, breadth and depth (number of people insured and services covered).
But yesterday, GPS demonstrated it's immunity and turned in coverage and discussion of surpassing depth and unconventionality.
Although our 400-hotspot panel showed good coverage and depth in the TCGA dataset, all patients could not be covered.
Second, in terms of scope and coverage and depth of commitments to trade liberalization it is one of the most comprehensive trade agreements and that too involving both developed and developing countries.
Our methodology will benefit substantially from increasing the number of biological replicates and the use of next-generation sequencing technologies (RNA-Seq) with appropriate coverage and depth, as in this study, mRNA of the control and treated groups were pooled (n = 3), while the confirmation by RT-PCR was done on individual samples (n = 3) in each of the groups.
The benefits packages need to be further studied to explore differences in coverage depth and efforts are required to reduce the differences in coverage height.
This issue is affected by multiple factors, including sufficient coverage depths for genome assemblies, characteristics of genome assemblers (e.g., tolerance of variance in coverage depths), and characteristics of datasets and genomes (e.g., read biases and genomic structures that affect assemblies will make the subset selection harder).
As different samples vary in genome coverage and sequencing depth, we used the HPB value (Additional file 4) to normalize the expression level for each transcribed site across samples, and selected a relatively higher cutoff at HPB > 5 for a given site, comparable to RPKM/FPKM > 5 for a gene, to call potential editing candidates in highly expressed sites.
Since tandem repeats are often missed by paired-end short-read sequencing technologies due to mapping errors, leading to changes in coverage depth in and around tandem repeats (30), we assessed coverage depth within the core 9p linkage region.
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