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Independent Student's t-tests were used to analyze differences in continuous measures between the age groups.
Treatment group differences in continuous measures were analysed with analysis of covariance, with baseline values as covariates.
Hence the focus is on change in continuous measures of lifestyle risk factors as the primary outcomes.
After assuming an autocorrelation of data r = .30, changes over time in continuous measures will be tested by paired t-tests.
Multivariable, adjusted 9-month changes in continuous measures will be assessed using linear regression in a manner similar to that detailed for the clinical outcome analysis.
Additionally, mean and SD were calculated by treatment arm on the Y4 change in the BMD of lumbar spine and total hip and the Y4 change in continuous measures of interest: weight, fitness, physical activity, and A1C.
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CMA was significantly lower in individuals with migrant background, compared to individuals with Swedish background.> -wrap-foot> Dinferencontinuoustinuous measure of medication acquisition (CMA) by exposure to generic substitution by each covariate analysed with ANCOVA.
CMA was significantly lower among individuals with migrant background, compared to individuals with Swedish background.> -wrap-foot> Dinferencontinuoustinuous measure of medication acquisition (CMA) for those who experienced generic substitution at first purchase, compared to subsequent substitution by each covariate, analysed with ANCOVA.
The secondary outcomes of change in the continuous measures of cognitive function and self-reported adherence will be analysed in the same way.
In principle, continuous measures of exposure to therapy, i.e. corrections based on duration and last time of use, could improve the power of TH as a covariate.
In correlation analyses, continuous measures of TBB in handwipes and dust were positively correlated (rp = 0.48; p < 0.001; rs = 0.34; p = 0.01), as were levels of TBPH (r p = 0.38; p < 0.001; rs = 0.35; p = 0.01).
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