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Drug application by mixing the substances with the food did not prove to be effective as the pellets were partly disregarded by the animals, resulting in considerable variations of plasma levels.
Administration of the same dose regimen of a specific anticancer drug or drug combination to a population of patients is likely to result in considerable variations of toxicities ranging from no side effect to potentially lethal events (Kuilenburg et al, 2001; Rothenberg et al, 2001).
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However, modern day concrete varies greatly in composition and rheology that result in considerable variation in setting behaviour.
It was observed that the liposome preparation process significantly affects liposome particle size, and this resulted in considerable variation in the drug encapsulation efficiency.
Adjustment of moisture at weekly intervals resulted in considerable variation in the moisture content of composts.
Others find training results in considerable variation in rater severity and scoring criteria (Lumley & McNamara, 1995; Orr, 2002; Papajohn, 2002).
The difficulty in distinguishing LCC from other NSCLC by routine histopathology results in considerable variation in the classification of NSCLC cases.
This results in considerable variation in the typical sun exposure and doses of UV radiation.
However, this resulted in considerable variation in practice, both between regions and within regions.
However the interventions in the ANC package provided through government health facilities were not consistently provided resulting in considerable variation in quality and uptake of ANC services [ 23].
This has resulted in considerable variation in important components such as education, and the notable absence of key features such as a home-based component or remote monitoring.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com