Sentence examples for in conditions of challenge from inspiring English sources

These results confirm that CXCR2 signalling supports articular cartilage homeostasis in vivo in conditions of challenge and demonstrate that its disruption is associated with more severe OA.

35 36 Therefore, SOX9 is strictly required for chondrogenesis, but, once chondrocytes are differentiated, it becomes only required in conditions of challenge.

Taken together, these data suggest that CXCR2 signalling protects chondrocytes from apoptosis in conditions of challenge by supporting AKT phosphorylation and SOX9 expression.

C-constrained MFA enabled quantitative determination of intracellular fluxes in conditions of different redox challenges without including redox cofactors in metabolite mass balances.

The monitoring of RhoGTPase activities in conditions of microgravity is still a challenge as it is a dynamic process that controls other highly dynamic processes such as actin polymerization or focal adhesion turnover.

Replication fork integrity is challenged in conditions of stress and protected by the Mec1/ATR checkpoint to preserve genome stability.

Pain management in conditions of chronic inflammation is a clinical challenge, and increasing our understanding of the mechanisms driving this type of pain is important.

I traveled to Würzburg, Germany, last week for a conference about the free press, where journalists from Russia, Turkey, Hungary and Poland, among other countries, spoke of the challenges of reporting in conditions of ever-increasing authoritarianism.

The many ongoing environmental changes, such as global climate change, use of agrochemicals and invasion of new species, result in stressful conditions, which challenge the persistence of natural populations and reduce biological diversity [e.g., [ 1]].

Despite that Q1 high, it had prepared investors for a Q2 slowdown — warning in April of challenging conditions ahead, citing weakness in the display panel segment and a decline in profitability on the mobile side, amid rising competition in the high-end smartphone segment.

It is possible that the buffers would play a more determined role in subjective wellbeing management under conditions of greater environmental challenge.