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Read clouds uncover variation in complex regions of the human genome.
Future applications will make use of the model's capabilities to conduct investigations in complex regions including the atria.
Within the structured grid approach, numerical solution of partial differential equations (PDE) in complex regions requires the decomposition of the domain into several zones.
Using a tiered frequency approach in concert with GISTIC provided a greater depth of understanding in complex regions for which there is no clear driver.
For the remaining 35 published inversions, 11 reside in complex regions consisting of multiple types of structural variants.
Furthermore, a systematic assessment of the utility and combination of different library insert sizes for resolving existing assembly difficulties in complex regions of genomes is currently lacking.
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In morphologically complex regions, such as the hippocampus and brain stem, co-registration may in theory be less optimal, which potentially could influence findings in these regions.
However, mapping ACD has proven challenging, particularly in spatially complex regions harboring a mosaic of land use activities, or in remote montane areas that are difficult to access and poorly understood ecologically.
However, LD with the best available SNP markers was weaker than has been reported for deletion polymorphisms in less complex regions of the genome.
We accounted for the LD between variants in the complex regions containing more than one independent SNP to avoid overestimating FRR.
Furthermore, targeted region sequencing may be of great utility in examining other such complex regions in fine detail in the future.
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