Sentence examples for in complex pathways from inspiring English sources
These results demonstrate that significant flux amplification in complex pathways involving central carbon metabolism is possible through coordinated overexpression of more than one gene in the pathway.
Depression associated with stress involves a number of body systems such as the neuroendocrine and neurotransmitter system and the immune system including cytokines and the dysregulation of the HPA axis interacting in complex pathways.
Genes may operate in complex pathways with gene environment and gene gene interactions [ 7].
It is possible that the statistically most significant genes are not the most important ones on a functional level considering an interplay of genes in complex pathways.
Yet, rare variants might be implicated in complex pathways as previous studies suggested their contribution to common disease (65) and their importance in several disorders (66– 66).
Given the limited success of identifying significant individual risk-conferring variants for some disorders, it is hoped that the discovery of responsible epistatic interactions among genetic variants reflecting molecular elements in complex pathways will elucidate novel disease mechanisms.
16 His1 is a tumor suppressor gene essential for mammalian development; it is epigenetically silenced in many human tumors and is involved in complex pathway regulating TP53 tumor suppression activity.
Brachial FMD and carotid IMT may indicate distinct and independent stages in the complex pathways leading to accelerated atherosclerosis in patients with RA.
Brachial FMD and carotid IMT values may indicate distinct and independent stages in the complex pathways leading to accelerated atherosclerosis in patients with RA.
Notable successes have been reported in altering complex pathways to improve plant quality and resistance to biotic and abiotic stresses.
For enzymes, it is much more informative to measure defined parameters (such as KD or Ki) that can be compared with computed binding constants, and can be used in modelling complex pathways.
