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Soy and isoflavone consumption had no effect on circulating total estradiol, estrone or SHBG concentrations in premenopausal women (on the basis of 6 11 studies per comparison, each comparison had over 200 women in combined control arms, combining with either SMD or MD, no suggestion of heterogeneity).
Soy isoflavones had no statistically significant effects on progesterone, circulating free estradiol or IGF-1 concentrations (where there were at least three studies and at least 50 women in combined control groups).
Soy isoflavone intake had no effect on FSH, LH, circulating estrone sulfate, circulating free estradiol, TSH, T4 or IGF-1 concentrations (where there were at least three studies and at least 50 women in combined control groups).
In post-menopausal women, there was a small increase in circulating total estradiol concentrations following soy isoflavone consumption, but this was not statistically significant (on the basis of 21 studies, 580 women in combined control groups, SMD 0.13, 95% CI −0.01 to 0.27, or an increase of 14%, 95% CI −1% to +29%, P = 0.07, I 29.3%), see Supplementary Fig. 1.
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Age-adjusted visual contrast sensitivity (VCS) was significantly lower and the presence of PEAS-associated symptoms was much higher in the estuary cohort (n = 77) than in combined-control cohorts (n = 87), one without exposure to bodies of water (n = 53) and one with exposure to marine waters (n = 34).
The incidence of aorticopulmonary septum-related defects in the combined control groups was 1/770 (0.1%); in the combined glyphosate-treated groups the incidence was 6/1939 (0.3%).
The time-corresponding cumulative hazards of the first occurring composite CVD end point, shown in figure 1, suggest that the risk of CVD was lower in the colectomy group than in the combined control group.
In line with this, students in the combined control groups assigned an average of 40.65 g of hot sauce or about six spoonfuls to the peer who had excluded them (Mcoping skills = 42.18, SD = 36.95; Mno treatment = 39.03, SD = 34.14), indicating high levels of aggression on the basis of previous studies using this measure (Lieberman et al., 1999).
The percentage of sites with attachment loss ≥ 3 mm was 2.2% in the combined control group compared to 3.2% in the preterm cases p =.21.
Three months postintervention, victimized students who had received the incremental theory intervention were 2.5 times more likely to be nominated by their teachers for reductions in conduct problems (such as aggression and acting out in class), relative to victimized adolescents in the combined control groups.
On the contrary, the two protective haplotypes were found at ∼42 47% in the combined control group, but at ∼31 43% in the combined case group.
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