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Such observations highlight the need to study the effects after long-term exposure to lower dosages and/or in combination with relevant herbicides as described above.
Therefore, there exists a need to fill these defects with a bridging (usually porous) material (termed scaffold), which should also, in combination with relevant cells and signaling molecules, promote the regeneration of new bone tissue.
Use of novel techniques including large‐scale genomics and proteomics in combination with relevant mouse models will most likely provide novel insights into the molecular mechanisms underlying glioma formation and will hopefully lead to development of treatment modalities for GBM.
Awareness of the normal anatomy and existence and common imaging presentation of these diseases, in combination with relevant clinical findings (clinical history, age, location and skin changes), enables the radiologist to make the correct diagnosis in most cases, thereby limiting the need for invasive procedures.
In a similar vein, accurate high-throughput segmentations could be used in combination with relevant features and machine learning methods to improve tumor grading in cases where grading is ambivalent (or to discover potentially useful distinctions within grades), and to provide a more accurate and patient-specific prognosis[4].
Yet, detailed information about proteins establishing DNA methylation or performing active DNA demethylation, in particular in combination with relevant expression data in various cells, is missing.
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The "Histone" dataset incorporates conserved nuclear H3 sequences from eight atyid genera, which were also analysed in combination with the relevant 16S sequence ("Combined 16S/H3").
One of the important milestones achieved in this study was to use 10 nm GNPs at a relatively low incubation concentration (0.3 nM) in combination with clinically relevant higher energy radiation (6 MV) while still causing damage to DNA.
Through the use of modern digital technologies and tools, and in combination with the relevant educational approach, a two-way knowledge communication between academia and industry is formed, aiming to mutually benefit both stakeholders.
Knowledge of the normal anatomy and existence and common presentation of these diseases, in combination with the relevant clinical findings (clinical history, age, location and skin changes), enables the radiologist to make the correct diagnosis in most cases, thereby limiting the need for invasive procedures.
In such cases, data from animal studies are used to develop models relating antibody level to protection probability in the animal, and then data from a study or studies in human subjects vaccinated with the proposed vaccine regimen are used in combination with the relevant animal models to predict protection in humans, and hence estimate vaccine efficacy.
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