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Deregulated HER family receptors, particularly HER3, and their downstream pathways are implicated in colonization of brain metastasis.
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We have analyzed a relatively large and rare set of human tumors to elucidate the mechanisms involved in colonization of the brain.
Members of foreign royalty are also making official visits to India — even royalty whose ancestors were involved in colonization of the subcontinent centuries ago.
Hence, this could be an important factor in breast cancer colonization of the brain and therefore a potential axis for future therapeutic intervention [ 41].
In addition to extravasation and homing through an endothelial cellular layer and to a specific matrix, the blood brain barrier (BBB) may be a limiting step for cell colonization of the brain (Cardoso et al, 2010).
A similar mechanism could function in cell survival, growth, proliferation and colonization, invasion and motility of metastatic tumor cells in the microenvironment of brain metastases [ 4, 5].
And there's definitely still plenty of territory to claim in the colonization of the mobile market.
Trade played a significant role in the colonization of India - largely for the benefit of Britain.
But do we realize that we promote similar beliefs in our colonization of other cultures and our imperialistic nationalistic demeanor?
This indicates that sinefungin inhibits in vivo colonization of pneumococci.
It was assumed that these altered gene expression profiles acquainted from a series of in vivo/ex vivo selections may facilitate the successful colonization in brain.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com