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These approaches are complementary: limma and other conventional microarray analyses are appropriate to detect genes that are differentially expressed in close to every single sample of a group, whereas Messina is optimised to detect differences between groups even if the differential expression is present at a low frequency.
Here, repetition of the main point of the paper is used in (close to) every sentence.
Similar(58)
At the Armory, the audience had leaned in close to catch every nuance.
O'Connor tells a wisp of a story, but in a voice so insistently stirring, you want to lean in close to catch every word.
("He had," he's convinced, "made her sick and sad"). O'Connor tells a wisp of a story, but in a voice so insistently stirring, you want to lean in close to catch every word.
At the Cooler, in his first New York concert in close to 20 years, every piece represented a discrete mood, and each connected him to the American minimalist tradition.
5 Evidence suggests that obesity is implicated in close to 3 million deaths worldwide every year.
Lean in close to talk to him.
Zoom in close to the art.
Get in close to your sparring partner.
Zoom in close to your art.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com