ACC has a close interconnection with the insula, thalamus, prefrontal cortex, and other subcortical structures, and is considered to be implicated in both affective and cognitive-attentional dimensions of pain and plays a deterministic role in pain modulation and analgesia [37].
In addition, the close interconnection of both trajectories is also mirrored by mutational studies that identified two conserved amino acids in the I-helix region of AOS.
With close interconnection of clinical and research units, the clinical topics are reflected in corresponding research modules (see below).
These results are consistent with a close interconnection of both enzymatic pathways as proposed before [ 25, 29, 30].
Abstract: The death of Turnus, which is depicted in terms evocative of sacrificial rite, evinces a close interconnection between ritual and poetics in Vergil's Aeneid.
Earlier studies on parents' vaccine decision-making in the UK have highlighted the close interconnection of parents' decisions on natural birth, breastfeeding and vaccination [ 10, 13, 19].
These findings, which clearly need to be investigated in more detail, are of potential relevance considering the close interconnection between pain, mood, sleep quality, and quality of life in the elderly.
Previous genetic and genomic studies have demonstrated that there is a close interconnection between the ILS and stress-response pathways in C. elegans [ 8, 28].
Preclinical studies have demonstrated a close interconnection of the RAS-RAF-MEK-ERK and the PI3K-AKT-mTOR signalling pathways, with complex inter-related feedback loops.
