Sentence examples for in cdr from inspiring English sources

In particular, two positions in CDR H2 (H58 and H59) greatly influenced antigen binding by controlling the pocket shape between CDR H2 and CDR L3 (Fig.  2).

Czf1 is likely to play an important role in CDR acquisition since its overexpression is a general feature of all the CDR strains that we have tested, but was not found in MDR strains.

In contrast, we found a negative correlation between SD and CDR in both groups (young = -0.477; aged = -0.455), which suggests that mice with better SD performed worse in CDR, irrespective of age.

Thus, the kink is a critical driver of the observed structural diversity in CDR H3.

In Section 5, we will focus on the abundant literature that has been produced on human mobility, made possible by the spatio-temporal information contained in CDR data.

However, in the general case, data about users in CDR databases is often missing, and census data may not always be available for comparison.

Additionally, two point mutations in CDR-L1 and CDR-L3 and three point mutations in CDR-H2 and CDR-H3 loops of the humanized scFv (huscFv) were introduced to increase affinity of the huscFv to EGFR.

In CDR-L1, sequences were more heterogeneous.

It might explain why during affinity maturation in the first round, similar advantageous sequences were selected in CDR-H1, while in CDR-L1 no consensus could be observed.

The sequence of these clones displayed 1 to 6 amino acid changes in CDR-H1, CDR-H3, and CDR-L3.

In general, the 10 sAB clones identified through this sorting process had high sequence and loop length diversity in CDR-H3.