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We found that miR-144 was significantly down-regulated in CCA tissues and CCA cell lines.
Mcl-1 is frequently overexpressed in CCA cells and human CCA tissues [ 10, 19, 20].
These data showed that RXRα is markedly overexpressed in CCA patients as well as in CCA cell lines.
A global increase in CCA related mortality and incidence of CCA have been reported [ 3, 4].
Exhilaratingly, matrine was found to greatly enhance RIP3 expression in CCA cells, which might solve the problem of chemoresistance in CCA treatment.
The functional role of Tβ10 in CCA cell migration and metastasis was studied in CCA cell lines and a nude mouse model of CCA xenograft.
"You've more things in CCA.
Matrine-induced necroptosis in CCA cells.
(b) Representative images of low RIP3 expression in CCA tissues.
(a) Representative images of negative RIP3 expression in CCA tissues.
(c) Representative images of strong RIP3 expression in CCA tissues.
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