In case of the psaC intron, considerable expansion was noted for the loop of domain VI (1,501 nt compared with 34 and 296 nt in Oedogonium and Stigeoclonium, respectively).
Overall precision scores, when compared to their corresponding recall values were considerable better in case of the CEM task (even more than in case of the CDI task).
It is widely assumed that scoliosis should not be treated conservatively but instead periodically observed and, in case of considerable progression to the threshold values of the curvature angle, surgical intervention is suggested [ 8].
In our next research, we will choose more samples in order to guarantee the sample size in case of considerable non response rates.
This results in a maximal sample size of 170 BCS that need to be included in the BREATH trial in case of considerable drop-out.
In case of considerable heterogeneity between study results that cannot be explained by the a priori defined subgroup and meta-regression analyses, a series of a posteriori (explorative) meta-regression analyses will be performed to identify sources of heterogeneity.
However, in case of considerable nutrient mobility from depot to seeds, it is advisable to place starter N farther from seeds to avoid harmful osmotic effects and ion toxicity [32].
In case of considerable heterogeneity (I2≥50%) a pooled estimate is not sensible and, therefore, was not calculated [32].
Only in case of considerable increases in ICP or in patients at high risk of nosocomial infections, a moderate elevation of the head of 15° to 30° is recommended, always depending on the CPP [ 34].
In case of considerable heterogeneity between study results in a specific comparison that cannot be explained by the defined subgroups, a series of a posteriori (explorative) meta-regression analyses will be performed to identify sources of heterogeneity.
