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In case of targeting of the two TRAIL death receptors, the therapeutic rational was initially apoptosis induction in tumor cells, but now there is evidence that the tumor vasculature is similarly a useful TRAIL target structure.
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These results demonstrate the validity of VariantMetaCaller also in case of target regions that are typical in targeted gene panels.
> In order to demonstrate the applicability of VariantMetaCaller on smaller genomic scales, especially in case of target region sizes that are typical in targeted gene panels, we filtered the full length chromosome to smaller non-overlapping regions, where the exonic length added up to approximately 100 kb, 200 kb, 300 kb and 500 kb, respectively.
In case of target present, a method for comparing detection performance of radar systems is proposed by evaluating its non-centrality parameter.
where ({chi _{2}^{2}} ) denotes the chi-square distribution whose DOF is 2. In case of target present, the non-centrality parameter is 2|α|2 s H R −1 s.
The subjects were instructed to press a button with the index finger of their dominant hand in case of target presentation.
More importantly, Paul seems genuinely interested in criminal justice reform, especially in the case of targeting minorities and mandatory minimum sentencing.
In the case of targeting VEGFR2, particles were placed in the periphery of the matrix.
This is of immense importance especially in the case of targeting toxic drugs to highly invasive brain tumors.
In the case of targeting PSMA expressed on the surface of PC-3/PIP cells, IRDye800-YC27 was used.
In case of CD70 targeting, it was the initial idea to exploit the tumor-associated expression of CD70 to direct antibody-dependent effector functions to tumor cells.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com