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These results demonstrate the validity of VariantMetaCaller also in case of target regions that are typical in targeted gene panels.
> In order to demonstrate the applicability of VariantMetaCaller on smaller genomic scales, especially in case of target region sizes that are typical in targeted gene panels, we filtered the full length chromosome to smaller non-overlapping regions, where the exonic length added up to approximately 100 kb, 200 kb, 300 kb and 500 kb, respectively.
In case of target present, a method for comparing detection performance of radar systems is proposed by evaluating its non-centrality parameter.
where ({chi _{2}^{2}} ) denotes the chi-square distribution whose DOF is 2. In case of target present, the non-centrality parameter is 2|α|2 s H R −1 s.
The subjects were instructed to press a button with the index finger of their dominant hand in case of target presentation.
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In case of targeting of the two TRAIL death receptors, the therapeutic rational was initially apoptosis induction in tumor cells, but now there is evidence that the tumor vasculature is similarly a useful TRAIL target structure.
In cases of target vessel occlusion on duplex scan, percutaneous transluminal angioplasty was repeated only in the presence of symptoms.
It is found that, in cases of targets with the same total thickness, the function of wearing and slowing down the projectile is mainly realized by the NS metal layer, while in cases of targets with a constant areal density, the function of wearing the projectile is mainly realized by the ceramic layer.
We have demonstrated its low sensitivity with respect to domain movements in case of multidomain target proteins, which allows for automated assessment without the need for manually splitting targets into AUs.
Successful performance in case of single target drugs, implies a potential to extend its capabilities to compounds bearing desired activity towards multiple receptors.
In case of ChEMBLPred target prediction models (10 μM) were downloaded from ChEMBL website and implemented locally using RDkit and python.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com