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In case of screening with the nanopill, 16.7% of the respondents would prefer not to be screened.
In case of screening HbA1c ≤8.0%, the sulfonylurea dose was decreased by ≥25% (or stopped in case of minimum dose) at randomization in order to decrease the risk of hypoglycaemia.
In case of screening for Pompe disease, according to professionals, advantages for both classic infantile and later manifesting, less severe, cases included health gain, avoiding a diagnostic quest, having a reproductive choice in future pregnancies, and the ability to gain more knowledge about the disease and treatment.
In case of screening HbA1c ≤7.5%, the insulin dose was reduced by 20%, otherwise the insulin dose was to be kept stable within ±20% of the screening dose and dose decreases were allowed in the case of two symptomatic or one severe hypoglycaemic event; increases of >20% for >7 days were considered as rescue therapy.
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In the case of screening positive in any of these tests, the women were followed up until a full diagnosis could be obtained.
Nevertheless, protection from cancer ofthe proximal colon seems to be less pronounced than for distal colorectal cancer even in cases of screening colonoscopy, which might be explained by lower detection rates of proximal compared with distal neoplasms 57 58 59 as well as differences in tumour biology.
In the case of screening mammography, she is usually only informed whether or not the acquired images are technically adequate.
In the case of screening for cervical cancer, for example, a "preventive health prompt" was in place.
In the case of screening with the nanopill, the percentage of people preferring not to be screened would be reduced from 19.2% (iFOBT) to 16.7%.
In the case of screening for diabetic retinopathy, regionally generated reminder lists to facilities were stopped at the time the incentive was withdrawn but supports were kept in place for cervical cancer screening.
In the case of screening for Pompe disease, however, the focus on childhood disorders would be loosened as Pompe disease is a broad-phenotype disorder and symptoms may present at any age, including in adulthood.
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