It has been shown that functional recording is an effective means of decreasing nonphylogenetic signal and may help to infer phylogeny in the case of problematic taxa [ 50].
Our definition seems to be approximately accurate in a majority of woody dicot leaves, but it may be more biased in the case of "problematic leaves"—that is, leaves with thick or lignified cuticle or hairs, weak vascularization, extremely large or small size, or atypical lobation or compounding.
In general, the prediction of transmembrane spans in case of MCF carriers is problematic since hydrophobic domains are present, however, confidence levels are below the assumed critical value.
The subsequent feasibility study however indicates that the assumption of a lognormal distribution is problematic in case of fire.
The reason is the tight amount of degrees of freedom in which this analysis is conducted, which would be problematic in case of estimating Eqs.
When presenting the statistical results we start with the main effects and continue with interactions, which can be problematic in case of strong interactive effects.
Granger causality mappings (which are based on the concept of temporal precedence) might be problematic in case of strong inter-regional variability of the haemodynamic response (David et al., 2008), e.g. in stroke patients with vascular abnormalities.
This conceptual model might also be applied in other cases of problematic scale-fragment evolution.
Pay close attention to the member who is most skeptical that a given condition will hold true; that person represents the greatest obstacle and, in the case of a problematic possibility, an extremely valuable obstacle to the selection and pursuit of the option.
This invites the objection, raised both by Tennant (1987: 236) and by Boolos (1987: 184) that in certain conspicuous cases there is no a priori justification for commitment to the existence of denotations for these terms, in the case of particularly problematic concepts Φ (such as self-identity).
