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An insult to the cellular blue print by several anticancer drugs initiates an orchestrated response coordinated by sensor, transducer and effector proteins that detect the damage and activate either a repair mechanism or an apoptotic program in case of overwhelming damage.
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However, in case of a disaster, these networks can be overwhelmed by a tremendous amount of requests which they can not cope with.
However, in case of a natural disaster or a malevolent attack, these networks can be overwhelmed by a tremendous amount of requests which they can not cope with.
The 10,000-song capacity of the iPod that makes it possible to have music as a perpetual soundtrack was years away; in the Walkman era, it took a bagful of tapes and batteries to keep things going, and indecisive types would find themselves trudging around with dozens of cassettes, just in case they were overwhelmed by the need to hear, say, that John Peel Festive 50 tape.
Our accountant, who prefers to remain anonyomous in case he is overwhelmed by a rush of more profitable business, knows all our secrets.
Normal protective mechanisms may be overwhelmed in cases of excessive free radical production; cellular damage will ensue in these situations unless additional free radical scavenging capabilities are available through dietary constituents or other exogenous sources.
Amidst the inspirational patriotic decorations, three grief counselors were standing by in case anyone got overwhelmed.
The national humanitarian response was immediate, and in some cases even overwhelming.
Correlations between CSF cytokine levels and other markers of inflammation were confirmed in severely ill cases, but not in critically ill cases overwhelmed by inflammatory responses.
In fact, the idea of fraudulent cases overwhelming the legal system is fiction.
But after the crisis produced massive numbers of delinquent homeowners, judges in many cases became overwhelmed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com