This index aims at comparing the ratio of non-synonymous (= amino acid changing) to synonymous (silent) changes within species (π n / π s ) and between species (D n / D s ): NI is one when evolution is neutral, higher than one under purifying selection, and lower than one in case of adaptation.
AM processes excel based on aspects like outstanding geometrical flexibility and lack of tooling, which allows significant lead time reductions both in initial product design and in case of design adaptations.
In case of device adaptation, the development challenge is related to the heterogeneity of the devices, which requires software engineers to create different versions for each type of device and every platform.
In case of quality adaptation, MME commands the MANE with the new parameters.
Various regularization methods are applied to improve performance in case of insufficient adaptation data.
In patients receiving the drug at longer intervals, in case of drug adaptation, blood sampling was made.
In[9], a speaker-space compressive sensing method is used to perform speaker adaptation using an over-complete speaker dictionary in case of limited amount of adaptation data.
In case of the appropriate adaptation of the discharge time point, it is possible to comply with the recommended dose limit of 1 mSv per year for the general public according to ICRP 103, even in the case of performing several therapy cycles per calendar year and patient.
In addition, in case of a small adaptation of an intervention that has already been proven effective and reimbursed, randomisation and a control group may also be hard to achieve.
