Sentence examples for in breast development from inspiring English sources

The gene expression of three genes and their "activation" signatures were compared to a panel of mammary cell lineage expression data, as well as breast tumor expression data, to help elucidate their role in breast development and breast tumorigenesis.

To understand the in vivo role of MUC1-CD in breast development, we generated a MUC1-CD transgenic mouse model under the control of the MMTV promoter in a C57BL/6J background, which is more resistant to breast tumor.

These observations in mice have led our group to develop a common cause hypothesis that asserts that misexpression of PTP1B, and potentially of other genes causing defects in breast development, may not only cause difficulties in breastfeeding but could also lead to increased risk for breast tumour formation and cancer progression.

The role of cyclin D1 in breast development and cancer has been well established.

Delays in breast development were also seen with hexachlorobenzene and DDE, including after adjustment for BMI.

Pin1 plays a pivotal role in breast development and may be a promising new anticancer target.

These antibodies may help us correlate receptor isoforms in both breast development and in cancer.

Notch receptor signaling pathways play an important role, not only in normal breast development but also in breast cancer development and progression.

These studies suggest the involvement of Notch signaling in normal breast development, and that alterations in Notch signaling may play a role in breast cancer development [ 15, 16].

Despite this remarkable change in adipocyte content and proportion, the precise role of adipocytes in normal breast development remains unclear.

Treatment with conjugated estrogens followed by progesterone replacement resulted in complete breast development and normal cycling.