Sentence examples for in both termini from inspiring English sources

In fact, we identified that miR-342 might be another example of Drosha processing shift because although its both strands are selected, the two strands do not make a typical ds-miRNA that has 2 nt overhang in both termini.

Following transcription, the extra sequences in both termini of pre-snoRNAs are degraded by ribonucleases [ 33].

Nonspecific digestion occurs when disconnection occurs at any amino acid in both termini, that is, equivalent to any substrings of the amino acid sequence.

In fact, both termini increase the low activity of the catalytic core (our data and [ 16]), and we speculate two mechanisms could be involved: they might increase the stability of the catalytic core, which would be consistent with the low long-term stability we observed especially for short Sirt1 constructs, and they seem to mediate dedicated regulation mechanisms.

In cases where both termini have functional roles, careful tagging in internal loops may be the only option.

The combination of circular dichroism, microelectrophoresis, and fluorescence quenching data showed that this peptide converted from a random coil in the aqueous phase to a "hammock" configuration in bilayers, with both termini exposed to the aqueous phase on the outside of the lipid vesicle and a central hydrophobic a -helical segment located near the hydrocarbon-water interface.

The route was designated in 1937, and both termini were rerouted.

The seipin protein has two transmembrane domains and resides in the endoplasmic reticulum (ER) membrane, with both termini in the cytoplasm [ 5, 6].

PEGylation at the C-terminus, regardless of the PEG size (30 kDa or 1239 Da) did not compromise the inhibitory potency of Poly R. In contrast, PEGylation at both termini (1239 Da) dramatically reduced its inhibitory activity.

The modification of both termini in Com7 gives mixed results compared to Com6 with an improvement in activity against B. subtilis, the same level of activity against S. aureus, and being less effective against E. coli.

As such, it is possible that the internal cleavage before Arg70 requires at least 5 flanking residues, while exopeptidases are involved in removing residues from both termini.