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16 The risk of bias was high in both systematic reviews.
Nine studies (n = 772) were included in both systematic review and meta-analysis.
However, the studies included in both systematic reviews primarily had small sample sizes, which were not population representative.
In the primary care setting, the findings highlight failures in both systematic AE assessment and reporting systems.
The possibility to simultaneously estimate rates and times in an efficient way is of great interest in comparative genomics, as well as in both systematic and evolutionary biology.
In two papers [ 12, 13] included in both systematic reviews a proportion of the patients were excluded from one systematic review converting, in one case [ 12], a relative risk favouring colloid to a relative risk favouring control.
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We have previously demonstrated that in the case of CTC enumeration by CellSearch this modified approach to ISR was exquisitely sensitive in differentiating between both systematic (bias) and random (imprecision) errors [ 15].
This means that justice agencies should have protocols in place that support both systematic identification of NSSI history as well as its management.
Potential sources of support should be clearly acknowledged in both the systematic review and the included studies.
Upon enrolment in both seasons, systematic recordings were made of the patients' demographic characteristics and medical history using standardised written questionnaires [ 21, 22].
We observed significant heterogeneity between studies included in both the systematic review as well as in the meta-analysis, which may be driven by differences in study design, construction of area level measures, and geographic units.
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