Exact(2)
We also discuss the potential relevance of insights gained from these approaches for enhancing islet cell survival and function in both major forms of diabetes.
Cells defective in BRCA1 are compromised in both major forms of DNA double-strand break (DSB) repair (nonhomologous end-joining (NHEJ) and homologous recombination repair (HRR)) as well as in cell cycle and transcriptional regulation [ 1- 7].
Similar(58)
We conclude that Nkx6.1 is among the very rare factors capable of stimulating beta-cell replication with retention or enhancement of function, properties that may be exploitable for expansion of beta-cell mass in treatment of both major forms of diabetes.
Increased β-cell death coupled with the inability to replicate existing β-cells drives the decline in β-cell mass observed in the progression of both major forms of diabetes.
In sum, the major forms of both AD and ATH are associated with vascular wall thickening and blood vessel occlusion.
Diabetes comes in two major forms.
It occurs in two major forms, caused by Trypanosoma brucei gambiense (T. b. gambiense) in West and Central Africa and Trypanosoma brucei rhodesiense (T. b. rhodesiense) in East and Southern Africa.
FN exists in two major forms.
Competition occurs in two major forms.
Chromium is found in the environment in two major forms: reduced CrIII and CrVI, or chromate.
The disease comes in two major forms: autosomal dominant and autosomal recessive.
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