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It showed a significant increase in birthweight of 135 grams.
Reports from Norway, Sweden and Canada using national data indicate a yearly increase in birthweight of approximately 3 g from about 1970 to 2000 [ 33, 34].
The combined effects of both the maternal and infant HFE H63 D variant genotype predicted a greater decrease in birthweight of 176.9 grams (95%CI: -318.6, -35.3).
IVF children derived from embryos that were cultured in two different media showed a significant difference in birthweight of almost 250 g (Dumoulin et al., 2010).
Previous reports have suggested that offering treatment to women with modest degrees of hyperglycaemia in pregnancy results in a reduction in birthweight of 100 140 g [ 13].
When both GSTT1– and GSTM1 null genotypes were considered, continuous maternal smoking during pregnancy was associated with a mean reduction of 340.4 g (P = 0.016) in birthweight of infants.
Similar(51)
The results were variable with no improvement in birthweight, rates of preterm delivery or smoking but an increase in breastfeeding duration and reduction in depression scores.
36 We hypothesise that metformin will reduce mean birth weight by 0.2 kg, corresponding to a reduction in birthweight centile of 0.33 SD.
There was no difference in the birthweight of patients compared to normals, but length and head circumference were significantly smaller in our patients.
Many studies showed a significant decrease in the birthweight of their children among smoking fathers [ 11- 16], while others demonstrated that paternal smoking did not decrease birthweight [ 17].
To detect a difference in mean birthweight of 100 g between the groups, a sample size of 211 for each group is needed.
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