Nevertheless, we have outlined how QUADOMICS can be tailored to suit the different phases of development and in such, any methodological shortcoming highlighted in our analysis was relevant considering the stage of development.
In addition, any methodological decisions (eg, choice of intra cluster coefficient (ICC) for re-analysis of cluster randomised trials or inclusion/exclusion of studies from analyses based on prespecified criteria such dropout rates >20%) taken in the course of preparing the review will be checked for stability of results in a sensitivity analysis.
On a more general note, we conclude that, in relation to any methodological approach certain assumptions and choices have to be made by individual researchers and often depend on ideological circumstances.
Actual cPRs/cDRs were calculated as cumulative numbers of pregnancies and deliveries in observed group of women without any methodological modification in relation to dropout patients.
24 25 In the absence of any methodological bias that could have artificially reduced the difference in efficacy between the two arms, we conclude that the answer to the question asked in the study 'Is the add-on strategy superior to the switch to monotherapy strategy?' is 'no' so that one could suggest that both strategies provide a similar benefit in terms of clinical and structural outcomes.
So when I say Streets of Rage 2 is my favorite game of all time, that's as much informed by my memories of playing it in the early 1990s than any methodological measuring of its qualities beside the thousands of other titles I've sat down with since.
Finally, we tested whether either differences in group size or any methodological steps (such as orthogonalization of PiB-uptake and intrinsic connectivity) could have influenced our results.
Hence, 20 patients were enrolled in this study in order to allow for any methodological difficulties that could lead to exclusion from the study.
Above all, establishing unequivocal evidence for the presence of metazoan clades in the late Neoproterozoic, as well as for the absence in more ancient strata, will probably have more impact than any methodological advance in improving the accuracy and precision of divergence time estimates for deep metazoan phylogeny.
The idea is that accurate scientific research should be replicable, and through replication we can also identify any methodological flaws in that research.
