Moreover, changes were in the anticipated directions (Table 3).
Furthermore, the estimated ORs move in the anticipated directions, i.e., away from the null.
Without prior evidence for change in behaviour in the anticipated direction, pursuit of a large and costly trial would be futile.
There were consistently small differences in the anticipated direction in comparisons with group 3, which were possibly as a result of chance, with P<0.1 for four of five comparisons for both groups 1 and 2. Restricting the sample to those scoring 2+ on AUDIT item 1 at follow-up diminished any small between-group differences (online Table DS2).
Correlational analyses supported the construct validity of the GRCD items, subscales, and total score and hypothesis tests in support of discriminating ability were in the anticipated direction and some were statistically significant, helping to verify the validity and usefulness of the GRCD.
In each case the correlation (+ or -) was in the anticipated direction.
However, the comparisons between the mab-5 gk670 mab-5 gk670-5(e1751)gof (2.2-folofincreand in gof, p = 0.0007) and between wild-type and the mab-5 e1751 gof mab-5 e1751 gofase in the gof, p = 0.001) were nominally significant and in the anticipated direction.
No significant differences were noted between the 2 groups in 6-minute walk distance or depression, although the changes were in the anticipated direction.
Although the exact patterns of weak, moderate, and strong correlations were not identical to what was hypothesized, relationships between GRCD items and the other measures were almost always in the anticipated direction and of the approximate size predicted.
As implied above, one clear cause of these minimal effects is the very weak correlation between ERS and achievement, which, while in the anticipated direction, is clearly too small to explain the moderate correlations between attitudes and achievement.
