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To determine if the TRAIL/DR5 pathway contributed to the apoptosis associated with differentiation in another established skeletal myoblast cell line, C2C12 myoblasts were transfected with pCDNA3-dnDR5 and G418 resistant clones were screened for the expression of FLAG-tagged dnDR5 (Fig. 5(C)).
To give our findings context in another established DENV mouse model, we also undertook experiments in IFN-α,β,γ-R−/− mice, since these mice can sustain replicating DENV infection for many days (Zellweger et al., 2010) and are a common model used for testing DENV anti-viral drugs (Rathore et al., 2011).
To test whether these KRAS PTEN pancreatic tumours show mTOR dependence, we compared response to mTOR inhibition in this model, to the response in another established model of pancreatic cancer, KRAS P53.
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In the N.F.C. title game, Smith will face another established quarterback in Aaron Rodgers of Green Bay or Eli Manning of the Giants.
Jesus eats and drinks with whores and highwaymen, turns water into wine, and, finally, in one way or another, establishes a mystical union at a feast through its humble instruments of bread and wine.
We've gotten to see one another establish ourselves in the world and become leaders in our fields.
To demonstrate the organ-specific role of TR3 in cardiac hypertrophy in vivo, we established another animal model in which endogenous TR3 was specifically knocked down in the left ventricle of the rats but not in other tissues (including the right ventricle, liver, muscle and kidney) by injecting lentivirus-packed siTR3 into the left ventricle (Supporting Information Fig S2A).
In another, to establish a context of sadness, men watched a scene from the movie "The Champ" after sniffing tears or saline.
We then searched for subclinical motor abnormalities, but the in-vivo electrophysiology as established in another treatment protocol [22], [23] did not reveal abnormal spinal transmission in all three experimental groups.
In 2004, Sanea established another bank in Bahrain, and that December he stepped down as managing director of T.I.B.C.: the central bank of Bahrain frowned upon individuals holding senior positions at multiple banks.
This is consistent with previously reported IRs of malignancy in another trial of abatacept in established disease 11 and in comparator RA cohorts treated with conventional DMARDs (0.67 1.77/100 patient-years).
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CEO of Professional Science Editing for Scientists @ prosciediting.com