In an endeavour to develop potent anti-tumor agents from betulinic acid (BA), a series of C-28 derived 1,2,3-triazolyl derivatives were designed and synthesized by employing Cu(I) catalyzed Huisgen 1,3-dipolar cycloaddition reaction.
Consequently, there is a pressing need to probe novel natural pharmacological agents in an endeavour to develop new drugs to address pediatric illnesses.
In an endeavour to develop new methods for cancer treatment, we developed the antagonists of GHRH (reviewed in Schally and Varga, 2006).
Our vision is that these individuals will, within 5 10 years, be leading many of the developing partnerships between higher-education institutes and health services; they will be bringing together academics, clinicians and managers from across sectors and disciplines in a common endeavour to develop the knowledge base that underpins improvement.
This background serves as the basis for a discussion of early breakthroughs and recent key developments in the endeavour to develop nanostructured materials as smart interfaces for fundamental cellular studies, tissue engineering and regenerative medicine.
In the endeavour to develop a model for studying gene therapy of cancers associated with human papillomaviruses (HPVs), mouse cells were transformed with the HPV type 16 (HPV16) and activated H-ras oncogenes.
The Minister of Social Development in Lesotho, Mrs. Matebatso Doti, said the findings of the impact evaluation will help Lesotho in its endeavour to develop a comprehensive social protection system for the country "The findings should not only be looked at in the context of the CGP, but should be viewed in the context of the bigger picture of social protection in Lesotho", she said.
In summary, SPIN is a unique endeavour to develop and test psychosocial and rehabilitation care interventions in SSc and to make these interventions accessible through patient organisations around the world with a low ongoing cost.
This was partly facilitated by the considerable administrative support from the Gangneung City council and health centres, especially as this study was part of a broader endeavour to develop a public oral health plan for the elderly in the area.
Clarification in the area of values — their nature, their origin, their role in consent — is sure to be an important prerequisite of future work in this domain, as scholars endeavour to develop improved theories, while at the same time being mindful of the need to address the practical exigencies of clinical reality with reliable and valid assessment tools.
For the past 12 years, the ALM, in partnership with IDRI, has invested US$4m into the endeavour to develop the vaccine and a new diagnostic test for leprosy.
