PPO in DEAE-Sephacel fraction with a Km of 2.43 mM might exist in an active form, which did not require any activators, e.g. trypsin, copper ion or SDS.
Extracellular Tat can enter cells in an active form [38], [43], leading to the activation of multiple signaling pathways including NF-κB and MAP kinase cascades.
HSP90 in cancer cells is present in an active form, in a multi-chaperone complex with high ATPase activity, in contrast to the HSP90 in normal cells, which is in an inactive, uncomplexed form.
PDGF-A and PDGF-B are secreted in an active form, whereas PDGF-C and PDGF-D demand extracellular proteolytic activation after being secreted.
Ligand-activated receptors interact with the p85 subunit, releasing the p110 subunit in an active form.
However, PPO in DEAE-Sephacel fraction more likely existed in an active form.
As mammalian cells, CHO cells produce mammalian-derived proteins in an active form, bearing appropriate modifications such as glycosylation.
This suggests that the liposomes are internalized and that calcipotriol is delivered intracellularly and released in an active form.
The BthChi74 gene products were expressed in E. coli in an active form, followed by purification to homogeneity through hydrophobic and anion exchange chromatography (Fig. 1b).
These nanoparticles have been tested for their ability to load proteins, to deliver them in an active form, and to transport them across the nasal and intestinal mucosae.
This enzyme is not expressed in an active form in man and evidence suggests that the presence of Neu5Gc in recombinant therapeutic glycoproteins may elicit an immune response.
