Currently there is no way for paraplegics to participate in the 100-meter dash, but all that may change if researchers succeed in restoring "brain-controlled ambulation" to the paralyzed.
Without treatment, the natural history of the condition is for affected boys to lose ambulation before the age of 13 and death in their late teens or early 20s due to respiratory or cardiac failure.
Progressive muscle weakness leads to loss of ambulation by the age of 10, and if untreated, to fatal cardiorespiratory insufficiency by the late teens.
Disease progression is severe, leading to loss of ambulation around the age of 10 and respiratory insufficiency necessitating night-time ventilatory support around the age of 20 years [ 1].
Progression of proximal muscle weakness, however, led to loss of independent ambulation by the age of 12 years in Cases 1, 2 and 7.
In contrast, the remaining GRMD dogs were usually able to maintain ambulation until their death and were classified as having a 'moderate form' of the disease (i.e. dogs with either a loss of ambulation after the age of 6 months or no loss of ambulation).
He developed progressive walking difficulties and lost independent ambulation at the age of 30 years.
The T100MW may be more sensitive to changes in ambulation capacity than the T25FW, and both tests appear to detect clinically meaningful improvements in ambulatory function.
The step from largely unimpaired ambulation to impaired ambulation status and the next step towards restriction to a wheelchair are not equal in distance.
The purpose of this study was to conduct a comprehensive analysis of the kinematic and kinetic profiles during ambulation that tests for the effect of walking speed in parallel to the effects of age, sex, and body mass index.
