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Screening a collection of Vietnamese S. suis ST1 strains [3] using PCR showed that the chromosome is found in alternative orientations in closely related strains, suggesting that the IS3-mediated recombination generating the chromosomal rearrangement is an ongoing process (data not shown).
that separate mitochondrial genome molecules exist in an individual, differing only in alternative orientations of the sequence of this loop or that the sequence on both strands of the DNA molecule is identical in this loop and therefore noncomplementary in double-stranded DNA.
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Alternatively, if the b domain plays a role in interactions between ERp27 and other chaperones or folding factors within the ER lumen, then the interdomain flexibility may be a positive factor in enabling alternative orientations for the domains in interactions with different partners.
Our results indicate that AA in the alternative orientation seems to be less stable, moving toward Arg120.
Although protein conjugates of Phase II metabolites have not been described, it is possible that reactive intermediates of DF might haptenize to proteins in an alternative orientation.
There is thus a challenge to clearly articulate where the alternative orientations lead, in both their processes and outcomes.
We abbreviate these alternative orientations as RCh and LCh.
However, BtMinpp also removes alternative phosphates from InsP6, indicating that the enzyme's active site can bind substrate in alternate orientations.
This year, Halifax's Dalhousie University had their first alternative orientation week named "Dreaming in Colour" hosted by the Black, Indigenous & People of Colour Caucus in partnership with the NSCAD University student union and Kings College student union.
Kinetic characterization revealed an 8-fold decrease in binding affinity for 33RE upon mutating Arg to Glu, suggesting an alternative orientation of this residue than that seen in the crystal structure.
This alternative orientation is expected to result in a steric clash between -JQ1 and amino acid side chains within the Bromodomain motif.
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