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In all variants, the dominant tautomeric state at neutral pH was the Nε2 state.
Notably, HL-1 cardiomyocytes showed good proliferation and metabolic activity in all variants out to 14 days in culture.
The passive transfer of sera obtained from immunized mice conferred full protection of naïve unirradiated as well as sublethally irradiated mice against low lethal doses of infection with F. tularensis LVS or strain 15, in all variants of the experiments.
Catalase activity decreased in all variants.
CAT activity decreased in all variants (Fig. 3).
In all variants a circulating autoantibody is found which binds to epidermal cells.
Similar(15)
MN14C11.6, a reference monoclonal antibody for serosubtype P1.7 epitope located in predicted loop 1 (VR1) identical in all the variants, was equally protective against all loop 4 variants.
The subgroups were tested for differences in all variant variables since the patients were clustered within the individual practices and selection artefacts can be assumed.
Fisher's exact test was used to compare the virus in the cluster to all variants identified in the study.
Exon-1 is present in all these 4 variants.
A recombination analysis showed four regions of recombination in all the 6B variants.
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