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Therefore, since simple scaling is the most straightforward approach and performs well compared to rank-invariant or cubic spline normalizations, we selected simple scaling as our method to employ in all further analyses.
Based on these reasons, we weighted fatality counts in the SI and Witham databases twice as strongly as those in the Munich RE and EM-DAT databases; the weighted figures were then averaged to give "best estimate" fatality figures, used in all further analyses.
We therefore pooled data for both women and men in all further analyses.
The two Instrumental subgroups were therefore combined in all further analyses.
The primer sets that resulted in the maximum and correct amplicon yield were used in all further analyses.
These three components were used in all further analyses.
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In addition, all further analyses were performed only on the common genes between the two miRNA targets sets.
Given that it is unlikely that the exclusion of the three items would yield a significant improvement in model fit in the subsequent CFAs, all further analyses were carried out on the IDS-SR30.
Furthermore, considering the computational efforts especially in the imputation process, all further analyses were not performed for the entire genome, but three chromosomes (chromosomes 3, 6 and 28) of different length were selected for the following analyses.
As it represented the relative increment in the GR at any time point compared with the baseline value, it was this 'change in GR' that was used for all further analyses, including incremental area under the curve (IAUC; calculated using the trapezoidal rule),15, 18 blood glucose response curve construction and statistics.
We carried out all further analyses in R 2.6.
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