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Repeat regions could result in artificial sequence similarity by being used as "seeds" in alignment process [21].
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Multiple-sequence alignment is a central issue in phylogenetic reconstruction, and errors in the alignment process often lead to errors in phylogenetic reconstruction [ 7].
For instance, UBERON, Neuro-Behaviour Ontology and Phenotypic Quality Ontology were applied in the alignment process (see step one in Figure 1 and section pairwise alignment of ontology concepts with OWLSim).
The distributed sequence aligner used in GensearchNGS currently only supports the GensearchNGS aligner algorithm and not external aligners such as BWA or Bowtie 2. It uses a stream based approach, where the client machine streams the data to be aligned to all computers involved in the alignment process.
For final gp120 alignments, a slightly modified protocol developed by Lamers et al. [50] using glycosylation motifs as anchors in the alignment process was used to maximize positional homology in gap-rich regions [50].
We varied which part of the terminology systems that we used to generate the resources, which parts that we word aligned and which types of resources we used in the alignment process to explore the influence the different terminology systems and resources have on the recall and precision.
By plotting the fraction of aligned reads against the number of differences maximally allowed in the alignment process (Fig. 1), we observed that the increase from perfectly matching reads to reads with up to four differences is not uniform.
We show how this framework can be used in the alignment process and explain how an alignment should be learned.
The number of particles of the particle filter used in the alignment process was set to 250.
During our experiments, it became clear that most classification errors were due to instability in the alignment process.
It was shown that emphasis on key interactions through the application of position specific weights in the alignment process significantly increases enrichment.
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CEO of Professional Science Editing for Scientists @ prosciediting.com