This finding suggests that the dementia of PD subjects is more likely due to a specific aSyn pathology rather than only an overlap of other pathologies, in agreement with post-mortem observations [ 17],[ 18].
Early reports implementing diffusion tensor methods reconstructed the bundle division of the OR (Catani et al. 2003), while more recent work using probabilistic approaches showed reliable estimation of the course of the OR in agreement with post-mortem descriptions (Sherbondy et al. 2008; Clatworthy et al. 2010; Hofer et al. 2010).
Note that, for the amorphous sample, the BD areas are smaller and the post-BD electrical conduction is lower, suggesting softer BD events, in agreement with the post-BD I-V curves.
Our strategy emphasizes that a gene should be defined as an element in the network of its interactions, in agreement with the post-genomic view of gene function [40].
In agreement with a post-replicative function, HLTF inactivation in a transgenic mouse disrupts cell cycle progression at the G2-M transition both in heart and brain cells [ 9, 10].
As shown in Additional file 2, our chemical genomic profiles revealed a large number of mutants in genes related to RNA metabolism, translation (ribosomal proteins), amino acid metabolism and protein modifications, in agreement with a post-translational regulation of the compensatory mechanism.
Testing of fabricated prototypes has given results in good agreement with post-layout simulated ones.
The suggested maturational order was in good agreement with post-mortem studies (Yakovlev and Lecours 1967; Flechsig 1920), confirming maturation of the sensory and motor pathways before association bundles.
These results are not in agreement with a scenario of post-glacial expansion from northern freshwater populations.
This is in agreement with previous reports of post-transcriptional regulation of these genes [ 42], showing a rapid increase in p53 protein concentration without de novo transcription which is particularly advantageous in cells with severely damaged genomes [ 43].
Further, these data are in agreement with previous reports that post-chemotherapy iron overload in adults with acute leukemia is not typically attributable to the inheritance of common HFE alleles [ 30, 31].
