Sentence examples for in aggressive forms from inspiring English sources

Our data uniquely indicate that CD22ΔE12 is a candidate driver lesion responsible for the activation of MAPK and PI3-K pathways in aggressive forms of B-lineage ALL.

The researchers demonstrated this concept by coating the polystyrene surface with antibodies that attack human epidermal growth factor receptor 2 (HER-2), a well-known target for cancer treatment since it is often over-expressed in aggressive forms of breast cancer.

In aggressive forms of mastocytosis, the accumulation of mast cells in organs and tissues causes a loss of function and degeneration, which can decrease life expectancy.

This finding is consistent with previous research showing alterations to matrix components such as versican [41] and alterations to GAG sulfation [42] in association with cancer, particularly in aggressive forms of cancer.

EZH2 expression was elevated in aggressive forms of PCa [ 31].

In contradistinction, primary calcification and intratumoral necrosis is seen in aggressive forms of non-Hodgkin lymphoma.

In our study, we show that Hsp27 is overexpressed in the aggressive forms of 53 human breast tumours.

As the chemokine receptor CCR5 is over-expressed in more aggressive forms of prostate cancer, and is also a critical receptor in inflammation, chemokine receptor CCR5 antagonists could potentially act as anti-prostate cancer agents.

"We urgently need to understand more about which men are at risk of developing prostate cancer and in particular aggressive forms of the disease.

Human ectopic viral integration site 1 (EVis) is an oncogenic transcription factor known to play a critical role in many aggressive forms of cancer.

The transcriptional repressor Bmi1, which is normally restricted to the stem-cell compartment, was found to be overexpressed in the aggressive forms of CML that progress to blast crisis within 3 years and during advanced phases of this disease (Chang et al., 2007).