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Given our problem statement of Sect. 2 and the corresponding model (2)–(4), we are interested in aggregate measures (market shares, total patronage etc).
There are also other approaches for the differential coexpression analysis of gene sets (Emmert-Streib, 2007; Freudenberg et al., 2010; Yu and Bai, 2011); the common aspect of all these approaches is that they account for changes in aggregate measures of pairwise correlations only.
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In aggregate, measured median data are reported in these studies for 66 different SVOCs whose octanol-air partition coefficients (Koa) span more than five orders of magnitude.
In terms of living conditions, South Africa actually outranks Ghana in most aggregate measures.
In general, aggregate measures of a city can largely depend on the city size.
The advancement of ageing can also be seen in terms of aggregate measures assessing its impact on population.
Because C. elegans is a hermaphroditic species, we assayed frequencies in hermaphrodite oogenesis, male spermatogenesis, and in an aggregate measure that combines hermaphrodite spermatogenesis and oogenesis.
If, however, there is significant heterogeneity in the areas used, then the aggregate measures can result in ecological fallacy when an association observed between variables at an aggregate level does not represent the association that exists at an individual level[ 7].
In our design, the two procedures generate aggregate measures that were in close agreement, however individual decisions were seldom consistent.
Although the bioaccumulation factor (BAF) is also used in the SC, other criteria for B, such as the biomagnification factor (BMF) and trophic magnification factor (TMF), have not been used explicitly, even though they are better descriptors because they incorporate the potential for dietary uptake and biotransformation in the aggregate measure of accumulation.
The reason is simple: Each CNV deletion can possibly account for only a tiny amount of total variation in the aggregate measure of infrequent deletions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com