Sentence examples for in aggregate formation from inspiring English sources

However, using a panel of fluorescently tagged variants of SOD1 in a cell model of mutant SOD1 aggregation, we demonstrate that the interactions between mutant and WT SOD1 in aggregate formation are not simply a co-assembly of mutant and WT proteins.

Localization of specific 14-3-3 14-3-3 14-3-3roteisoformsgates suggest that 14-3-3 proteins proteinpaggregatesregate formation or that their normal protective functionsuggeste disrupthatthrough 14-3-3 14-3-3 14-3-3

The role of moderate shear in aggregate formation is well represented by the model.

In AD patients, these aggregates are often found to be tightly associated with neuronal GM1 ganglioside lipids, suggesting an involvement of GM1 not only in aggregate formation but also in neurotoxic events.

The intrinsic and extrinsic factors that control soil aggregate formation have been widely studied at the aggregate scale, but little is known about their roles in aggregate formation at different landscape scales.

Thus nitration might have some role in aggregate formation in ALS.

Despite sharing over 99%% sequence similarity with each other in 16S rRNA genes (Ibrahim et al. 2010), these isolates showed some differences in aggregates formation, colony morphology, color, and size.

Expression of two prefibrillar, structure-based design mutants of αSynuclein (i.e., A56P and A30P/A56P/A76P) resulted in less aggregate formation in nigral DA neurons as compared to human wild-type (WT) or the inherited A30P mutation.

This scenario may explain the puzzling relationship between protein aggregation and cell toxicity, in that aggregate formation does not necessarily result in cell death.

Collectively, there is no simple explanation for how all the known missense mutations in αS result in PD and their divergent effects on in vitro aggregate formation suggest that conformational templating cannot solely account for disease progression.

While exposed extracellular matrix proteins play an essential role in mediating the first steps of platelet recruitment in damaged vessels, fibrinogen plays a predominant role in platelet aggregate formation.