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In experimental studies, SZRD showed the hypnotic effect on sleep enhancement and its underlying mechanisms may be mediated through the activation of serotonergic system in additional to the activation of Gamma-aminobutyric acid A (GABAA) receptors in rat [ 17, 18].
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In addition to the activation signature, additional miRNAs are differently expressed in CLL compared to untransformed B cells.
Thus, we have assumed additional steps in the model corresponding to the activation of the solid sucrose by the catalyst and autocatalytic steps.
Gene expression analysis of EGFR-stimulated rat ONHAs revealed additional commonalities in the activation of genes related to cell migration, ECM reorganization and immune response [ 47].
However, our results show that apart from the conventional conserved residues, additional residues in the activation loop may also play a crucial role in kinase activation.
In this process, two additional dc arcs are discharged between plasmatron and both the wire and the substrate, resulting in additional activation of the substrate and the particles, particularly by increasing their temperature.
Thus PARP activity has an additional role in both the activation and shutdown of promoter activity.
In addition, binding to the zona pellucida causes additional activation of cAMP/PKA and protein kinase C (PKC) [ 68– 70].
Thereafter, destruction of BubR1 might result in additional activation of the APC/C Cdc20 complex.
Taken together, these data suggest a possible WFA-induced vicious cycle, wherein WFA binding to vimentin elicits its degradation by caspases and said degradation results in additional caspase activation and apoptosis.
In order for the activation to precede additional costimulatory signals, such as ligation of the CD28/B7, CD4/HLA class II and CD/HLA class I antigens are required.
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