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These areas include the further refinement of the implementation requirements for WLC in additional case study settings and the need for simulation studies to verify the effectiveness of some of the proposed changes to the underlying theory of WLC.
Similar qualitative results were all also confirmed in additional case studies based on both the ENBF and ENCF models.
Markers rs1217414 and rs3789604 were genotyped in additional case and control samples (n = 253 and n = 2024, respectively).
Thirdly, we demonstrate in additional case studies that GGEA can be applied to human regulatory pathways, where it sensitively detects very specific regulation processes, which are altered in tumors of the central nervous system.
The variant resulting in a R47H substitution was identified to confer the greatest association with AD, which was further confirmed through meta-analysis of statistics from genome-wide association studies as well as genotyping this variant in additional case and control samples.
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Just how much strength the Second Amendment has in places that regulate but do not ban guns outright will be worked out in additional cases.
Most previous studies have been carried out on a single small cohort of KD patients, and findings were reported without validation in additional case-control sets.
Equally importantly, we also genotyped the selected SNPs in additional case-control and families for finding potential new T1D associations.
We tested whether the SNPs in Table 6 were associated with T1D in additional case-control and family data.
Taken together, these observations suggest that the potential link between MORF4L1 and risk of BrCa warrants further assessment in larger sets of BRCA2 mutations and in additional case-control studies.
The SNPs showing the strongest association in the GWA were analyzed in additional case-control cohorts 700 SNPs were successfully genotyped in cohort 2. Of these, 23 were nominally associated with obesity with consistent effect direction as observed for the GWA (additional file 1, Table S2).
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