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mTOR and TSC2 (tuberin, an upstream regulator of mTOR) also regulates cell cycle progression through the upregulation and stabilization of p27 [37]–[39], in addition to their function in protein synthesis through p70S6K and 4E-BP1.
In addition to their function as actin-crosslinking proteins, α-actinins have been found to interact with a large number of protein partners, and to play multiple roles in cells, including linking of the cytoskeleton to various transmembrane proteins, diverse signaling pathways, and regulating the activity of a variety of receptors [26].
This suggests these proteins may have independent function(s) in addition to their function as heterodimers.
In addition to their function in stress responses, HSFs also play critical roles in normal development (Abane & Mezger, 2010).
In addition to their function in the defense against infection, NETs may contribute to the pathogenesis of rheumatic disease.
In addition to their function in hemostasis, platelets are also involved in inflammatory disease and cancer [ 29].
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In addition to their functions in ovarian physiology, ER stress and the UPR may also play a role in ovarian pathology.
Several reports have stated that, in roots, the SOS proteins may have novel roles in addition to their functions in sodium homeostasis.
In addition to their functions as native ecosystem engineers (Jones et al. 1997), biotic soil crusts support a great diversity of lichens and bryophytes (Root et al. 2011).
In addition to their functions of financial planning, projection, and oversight, government budgets can also be understood as moral documents because, in the final analysis, every budget reflects the values of those who craft them.
In addition to their functions in development, stem cells play key roles in degenerative disease, aging, and oncogenesis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com