In addition to the well-recognized role in controlling vascular permeability, VE-cadherin and associated junctional proteins form part of complex signaling cascades regulating important cellular functions [ 6].
In addition to the well-recognized risks for insulin resistance, elevated concentrations of large, neutral amino acids were independently associated with insulin resistance.
In addition to the well-recognized effect of CR on longevity and disease, there is growing evidence that the abundance of individual nutrients, macronutrient types, and nutritional supplements (i.e., non-caloric dietary compounds) specifically influence health and longevity.
Floodwater chemical and physical properties, in addition to the well-recognized importance of seasonal timing, duration, depth and frequency of floods (e.g. Vervuren et al. 2003), will influence plant growth and survival during submergence.
In addition to the well-recognized microRNAs, recent studies have also shown that epigenetic silencing by CpG island hypermethylation of other classes of non-coding RNAs, such as transcribed ultraconserved regions (T-UCRs) or small nucleolar RNAs (snoRNAs), also occur in human neoplasia.
It also expands our knowledge that X chromosome plays an important role in pubertal development, in addition to its well recognized determination of sex.
In addition to its well recognized effects as a potent endogenous vasoconstrictor and smooth muscle mitogen, ET-1 also appears to have proangiogenic effects in some rheumatic diseases.
In addition to the recognized morbidity and mortality that can result from overt viral infections, lower viral loads that do not produce visible symptoms might nonetheless impact colony health as well.
In addition to the correlation due to overlapping genes, it is well recognized that pathways do not function as discrete elements, but rather are organized into cascades and co-regulatory networks.
In addition to the known GCN4 binding motif, OsSMF1 also recognizes the ATGA and ACGT motifs.
