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We analyze a mathematical model to investigate the consequences of both avenues of transmission on colony survival in addition to the efficacy of disease control strategies.
In addition to the efficacy, patient-reported outcomes (PROs) and tolerability need to be assessed to define treatment benefit, as PROs measure the patient's subjective experience and can be correlated with hard outcomes.
The rate of emergence of phage-resistant mutants was lower for phage phT4A when compared with phage ECA2 and phage cocktail phT4A/ECA2.The results indicate that in addition to the efficacy, the potential development of phage-resistant mutants must also be considered in the design of phage cocktails.
Harris et al. underlined the great esthetic outcome in addition to the efficacy of substitutive matrices for soft tissue [25].
SPF with no adverse events (SNAE) goes a step further, taking into account tolerability in addition to the efficacy of treatments.
In addition to the efficacy of IPTi, the costs associated with introducing and successfully delivering the intervention as part of an integrated health system have been studied in detail [7], as have the policy implications of introducing and sustaining the delivery of IPTi [2], [8], [9] and the perceptions of the communities who have received IPTi[10], [11].
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In addition to the high efficacy of wP against whooping cough, numerous works have described its efficacy as adjuvant when administered in combination with different antigens [36], [37].
In addition to the acoustic efficacy of such a wearing course system, the structural feasibility as well as the durability of the concept are subjects of the analysis.
36 In addition to the virologic efficacy, analysis from the DUET trials has shown a significant reduction in the hospitalization rate and in the number of hospitalization days among patients enrolled in the etravirine arm compared with the placebo arm.
In addition to the promising efficacy in HER2-positive breast cancer, use of lapatinib in HER2-negative diseases, especially in triple-negative cancers due to its frequent EGFR overexpression, is of interest and being tested currently [ 21, 22] but has been found to elicit diverse effects in different subgroups [ 8, 14, 39, 40].
In addition to the clinical efficacy of the combined therapy with vemurafenib and panitumumab described here, Al-Marrawi et al. recently reported that treatment of a single patient with a combination of sorafenib and cetuximab led to a mixed radiographic response with some areas showing dramatic improvement and other areas showing stable disease over a 7-mo period.
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