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The effect of NDGA on the filamentous actin cytoskeleton was comparable to that of cytochalasin D. However, in addition to the disruption of actin stress fibres, cytochalasin D also disrupted the circumferential actin filament network.
In addition to the disruption of the membrane phospholipid architecture, LP results in the formation of cytotoxic aldehyde-containing products that bind to cellular proteins and impair their normal functions.
In addition to the disruption of cell polarity, an upregulation of vimentin was observed following NEU-treatment.
In addition to the disruption of family routines during the illness, Taiwanese parents also complained about routine difficulties afterward (Vietnamese parents did not report on this aspect).
In addition to the disruption of genomic sequence through nucleases, CRISPR/Cas9 may be provided with effector domains that exert distinct regulatory functions.
In addition to the disruption of hydrogen bonding, proline, cysteine and glycine possess much smaller amino acid side-chains than arginine; therefore, the area of the DNA-protein interface was reduced with these mutations.
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Chaos ensued, not least because, in addition to the artificial disruption, there was a real one: a Tube train broke down on the Northern Line.
In addition to the uroepithelial disruption, visceral inflammation also remains a central pathological process in BPS/IC and has been suggested to underlie the development of LUT symptoms.
In a similar manner, the differential cleavage of fodrin by Pet and EspC could trigger different biological events in addition to the shared disruption of filamentous actin.
What sane people should be emphasizing is that in addition to the risk of financial disruption, there's the certainty of huge pain from spending cuts and a crippling hit to economic growth.
In addition to the influence of HPV, disruption of the endothelium in ARDS results in an alteration in the normal balance of mediators of vasodilation (NO, prostacyclin) and vasoconstriction (thromboxane, leukotrienes, endothelin, serotonin, angiotensin II) favouring vasoconstriction.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com