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He then began ordering blank hexagon mapping sheets so that he could create his own games, and soon was looking for innovative ways to do so - he introduced the use of dice of all five platonic solid shapes in addition to the common dice.
Thus, in addition to the inputs received by SOber, Dice needs a set of structure dictionaries ({overset {circ }{mathbf {D}}^{left (frac {N}{2}right)}_{l}|_{l=1}^{n_{nu }}}), one dictionary for each delay value ν l that is to be considered in the recovery process.
In addition to the latter function, miRNAs and other Dicer substrates direct DNA methylation to specific sequences in various organisms including mammals [ 31, 32].
To evaluate the segmentation accuracy of the different methods, we compared volume changes, which is a commonly used method, in addition to the spatial overlap index (SOI), a quantity similar to the Dice similarity coefficient.
Our results suggest that Dicer recognizes the loop/bulge structure in addition to the ends of shRNAs/pre-miRNAs for accurate processing.
However, in contrast to SOber, Dice facilitates the use of further prior knowledge in addition to the CA's sparsity in the recovery process.
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In addition to the above requirements, sequencing of both miRNA and miRNA* required that the miRNA/miRNA* duplex had 3' overhangs at both ends, a typical feature of Drosha and Dicer processing.
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