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But, in addition to sympathetic comments by Justice Anthony Kennedy during the argument of the Wisconsin case, there is another reason for optimism.
Although we are unable to explain our contradictory findings, many factors may have contributed to increased postoperative pain, in addition to sympathetic tone activation [12].
In addition to sympathetic activation, cardiac injury also leads to remodeling of the myocardium.
We have also observed, as have other investigators 1 in studies of this rather common disorder, that patients have multisystem complaints such as gastrointestinal motility disorders, distal paresthesias, heat intolerance with hyper- and hypohidrosis, in addition to sympathetic, and parasympathetic dysfunction.
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In addition to the sympathetic nervous system, the parasympathetic nervous system is also important in immune regulation.
In addition to the sympathetic hypoactivity observed during maximal exercise, cardiac autonomic impairment was noted following exercise, as suggested by a delayed deltaHRR recovery, which is initially affected by parasympathetic reactivation followed by sympathetic withdrawal.
In addition to sustained sympathetic activity, this increased heart rate could be interpreted as an inability to retain fluids (limiting plasma volume expansion) as a consequence of excessive dehydration.
In addition to increased sympathetic nervous activity, CFS patients are also characterized by slight inflammatory activation [ 28] and elevated nocturnal blood pressure and heart rate [ 53], which in turn are associated with development of atherosclerosis.
This may maintain the observed reduction in PVRI via distension of pulmonary vessels and pulmonary capillary reserve recruitment [29], in addition to the loss of sympathetic vasoconstriction.
In addition to the pain syndrome, sympathetic hyperactivity may explain other typical manifestations of FM such as sleep problems, irritable bowel, sicca symptoms, and anxiety [ 8].
In fact, during intense sympathetic stimulation, endogenous dopamine (in addition to noradrenaline and adrenaline) is secreted and serves to modulate sympathetic discharge [ 70].
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