Oxidative tumor cells can use lactate instead of (or in addition to) glucose, thereby sparing available glucose, which can, in turn, diffuse deeper into the tumor to fuel hypoxic cells located farther away from tumor blood vessels (Sonveaux et al., 2008).
Objectives: In addition to blood-sparing effects, aprotinin may have cardioprotective and anti-inflammatory effects during cardiopulmonary bypass assisted cardiac surgery.
Compared to conventional WBRT, in addition to the intended sparing of the Hippocampus, HS-WBRT delivered significantly lower mean dose (22.42 cGy vs. 16.33 cGy, p < 0.0001), V24 (9 cc vs. 44 cc, p < 0.0000) and V30 (9 cc vs. 0.096 cc, p = 0.0106) to follicle hair bearing scalp and prevented alopecia.
In addition to antigen dose-sparing, adjuvantation of inactivated split H5N1 vaccine promotes broad and persistent cross-clade immunity which is a pre-requisite for a pre-pandemic vaccine.
In fact, in addition to the NSAID-sparing effect of etanercept, this study also demonstrated a symptomatic treatment effect of etanercept over placebo similar to that observed in conventional clinical trials in which NSAID intake was mandatory at baseline and stable NSAID levels were required during the double-blind period.
However, recent work has provided evidence that, in addition to the commonly discussed function of providing or sparing energy substrates for neurons, astrocytic glycogenolysis contributes to the ATP pool of astrocytes themselves, energetically supporting astrocytic signal transduction [ 7, 8].
In patients with axSpA, etanercept was associated with clinically relevant NSAID-sparing effects in addition to significant improvements in conventional clinical outcomes.
In addition to the original eight charges, Manafort admitted to another two, sparing him from another trial.
Although there are no data from randomized controlled trials which define the structure-sparing effect of tocilizumab in addition to its well-established anti-inflammatory effect [ 30, 31], one can anticipate such an effect based on the observation that IL-6 drives RANKL expression and thus supports osteoclastogenesis [ 32].
In the future, in addition to examining the irrigation and aspiration of the phacoemulsification probe, we recommend sparing a few seconds to inspect the phacoemulsification sleeve for leaks or cracks.
