Sentence examples for in addition to notch from inspiring English sources

Different GSIs were used in the various studies including DAPT (Monsalve et al., 2009; Tsao et al., 2011), IL-CHO (Palaga et al., 2008), GSI-I (Narayana and Balaji 2008; Bansal et al., 2009) GSI IX (Wang et al., 2010) or GSI X (Tsao et al., 2011) and GSIs have been shown to affect signaling pathways in addition to Notch (Hass et al., 2009).

In addition to NOTCH, a second target we considered was TLX1 itself.

In addition to Notch signaling, Fgf8 and Wnt3a regulate nodal expression in the mouse node [13], [14].

In addition to Notch signaling, the expression of Id proteins is positively regulated by TGFβ/BMP signaling in different tissues [41], contributing to the balance of transcription factor availability (Fig. 12B).

In addition to Notch signaling, the canonical Wnt/ β-catenin signaling pathway has been reported to play a key role in cardiac stem-cell niche regulation.

Nevertheless, GSIs could block other functions in the cell other than Notch signaling, since γ-secretase targets other proteins in addition to Notch components [ 14].

In addition to the NOTCH pathway, we found that mutations in genes involved in several major metabolic pathways were significantly enriched in the stage I group.

For example, the analysis indicated upregulation by NKX3.1 of the p53 and IL1 pathways, in addition to the Notch signaling pathway.

In addition to the Notch pathway-dependent CSL proteins of the RBP-Jκ type, at least in some metazoan species, CSL transcription factors called RBP-L can be found, which are only beginning to be characterized.

In addition to the Notch receptor family, the gamma-secretase complex regulates the expression of ErbB4, CD44, and E cadherin, cell-surface receptors known to contribute to tumor growth, migration, and invasion [ 28- 30].

They also show that Notch-driven activation requires C2 domain activity in addition to canonical Notch-ligand binding.